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Applying Exchange 2010 RU21 to servers running RU16

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Applying Exchange 2010 RU21 to servers running RU16 - 27.Oct.2018 10:45:26 PM   
dding0919

 

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Joined: 20.Dec.2010
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I have 8 servers which are still running SP3 RU16. Need to upgrade them to RU21 (I know the most current is RU22 but decided to go to RU21). I have some questions:

1. Can I upgrade directly from RU21 from RU16? Should I go to a lower version first?

2. Is there anything I need to backup before applying RU21? I recall when I applied an upgrade in the past (don't remember if it's a SP or RU) the IIS settings were reset back to default. I lost all custom configuration.

3. I won't be able to apply RU21 on all servers at one night. It might take 2-3 nights. Can I run servers mixed with different RU level?

4. Is there any caveats I need to be careful?



Thanks in advance.
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